Author

A. V. Kabanov

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Pharmacology & Toxicology· 3 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:drug response / drug discovery· 5 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1

Frequent Co-Authors

C. Lim· 6 shared D. Hwang· 5 shared J. D. Ramsey· 4 shared M. Sokolsky· 3 shared M. Sokolsky-Papkov· 2 shared N. Vinod· 2 shared A. E. D. Van Swearingen· 1 shared A. Finkelstein· 1 shared

Activity by Year

2018-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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6 shared papersBioengineering

C. Lim

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Poly(2-oxazoline)-based polyplexes as a PEG-free plasmid DNA delivery platform

D. Yamaleyeva, N. Makita, D. Hwang, M. Haney, R. Jordan, A. V. Kabanov

This study develops PEG-free poly(2-oxazoline) copolymers for efficient plasmid DNA delivery to immune cells, finding that DET-based diblock copolymers outperform other structures in macrophage transfection.

bioRxiv · Dec 18, 2022Bioengineering

PEG-Free Polyion Complex Nanocarriers for Brain Derived Neurotrophic Factor

J. M. Fay, C. Lim, A. Finkelstein, E. V. Batrakova, A. V. Kabanov

This paper reformulates PEG-based polyion complex nanocarriers for BDNF with non-PEG polymers, maintaining self-assembly and receptor accessibility without compromising stability.

bioRxiv · May 23, 2022Bioengineering

Nanoformulated Remdesivir with Extremely Low Content of Poly(2-oxazoline) - Based Stabilizer for Aerosol Treatment of COVID-19

J. D. Ramsey, I. E. Stewart, E. A. Madden, C. Lim, D. Hwang, M. T. Heise, A. J. Hickey, A. V. Kabanov

bioRxiv · Jan 21, 2022Bioengineering

Bioequivalence Assessment of High-Capacity Polymeric Micelle Nanoformulation of Paclitaxel and Abraxane(R) in Rodent and Non-Human Primate Models Using a Stable Isotope Tracer Assay

D. Hwang, N. Vinod, S. L. Skoczen, J. D. Ramsey, K. S. Snapp, S. A. Montgomery, M. Wang, C. Lim, J. E. Frank, M. Sokolsky-Papkov, Z. Li, H. Yuan, S. T. Stern, A. V. Kabanov

Biomaterials · Nov 1, 2021Peer-reviewedPharmacology & Toxicology

Drug-dependent morphological transitions in spherical and worm-like polymeric micelles define stability and pharmacological performance of micellar drugs

C. Lim, J. D. Ramsey, D. K. Hwang, S. C. M. Teixeira, C.-D. Poon, J. D. Strauss, M. Sokolsky, A. V. Kabanov

This study evaluates how the morphology of polymeric micelles affects their pharmacological performance, finding that spherical micelles are more effective for drug delivery when drugs are loosely associated.

bioRxiv · Jun 10, 2021Pharmacology & Toxicology

Enhancing CDK4/6 inhibitor therapy for medulloblastoma using nanoparticle delivery and scRNA-seq-guided combination with sapanisertib

C. Lim, T. Dismuke, D. Malawsky, J. D. Ramsey, D. Hwang, V. L. Godfrey, A. V. Kabanov, T. R. Gershon, M. Sokolsky

This study improves CDK4/6 inhibitor therapy for medulloblastoma by combining nanoparticle delivery with scRNA-seq-guided identification of sapanisertib, enhancing survival in mice.

bioRxiv · Jun 9, 2021Cancer Biology

High Capacity poly(2-oxazoline) formulation of TLR 7/8 agonist extends survival in a chemo-insensitive, metastatic model of Lung Adenocarcinoma

N. Vinod, D. Hwang, S. H. Azam, A. E. D. Van Swearingen, E. Wayne, S. C. Fussell, M. Sokolsky-Papkov, C. V. Pecot, A. V. Kabanov

This study shows that a novel nanomicellar formulation of Resiquimod extends survival in a metastatic lung adenocarcinoma model more effectively than chemotherapy and anti-PD1 therapy.

bioRxiv · Dec 12, 2019Pharmacology & Toxicology

Bacteria boost mammalian host NAD metabolism by engaging the deamidated biosynthesis pathway

I. Shats, J. Liu, J. G. Williams, L. J. Deterding, C. Lim, E. Lee, W. Fan, M. Sokolsky, A. V. Kabanov, J. Locasale, X. Li

This paper shows bacteria enhance mammalian NAD metabolism by using a deamidated biosynthesis pathway, contributing to drug resistance and improving NAD-boosting efficiency.

bioRxiv · Dec 7, 2018Biochemistry