Author

J. D. Strauss

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1

Frequent Co-Authors

A. Bielecka· 1 shared A. F. Porto· 1 shared A. Urban· 1 shared A. V. Kabanov· 1 shared C. Lim· 1 shared C.-D. Poon· 1 shared D. K. Hwang· 1 shared F. M. Lobo· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperImmunology

A. Bielecka

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Author profile →

3 papers

Recent·Most cited

Mouse model and human patient data suggest critical roles for Pten and p53 in suppressing POLE mutant tumor development

V. S. Park, M. J. Sun, W. D. Frey, L. G. Williams, K. P. Hodel, J. D. Strauss, S. J. Wellens, J. G. Jackson, Z. F. Pursell

The paper shows that Pten and p53 loss contribute to POLE mutant tumor growth, but not mutation burden, in mice and humans.

bioRxiv · Oct 10, 2021 · PreprintCancer Biology

Drug-dependent morphological transitions in spherical and worm-like polymeric micelles define stability and pharmacological performance of micellar drugs

C. Lim, J. D. Ramsey, D. K. Hwang, S. C. M. Teixeira, C.-D. Poon, J. D. Strauss, M. Sokolsky, A. V. Kabanov

This study evaluates how the morphology of polymeric micelles affects their pharmacological performance, finding that spherical micelles are more effective for drug delivery when drugs are loosely associated.

bioRxiv · Jun 10, 2021Pharmacology & Toxicology

IgA-deficient humans exhibit gut microbiota dysbiosis despite production of compensatory IgM

J. R. Catanzaro, J. D. Strauss, A. Bielecka, A. F. Porto, F. M. Lobo, A. Urban, W. B. Schofield, N. Palm

This study shows that IgA deficiency in humans leads to gut microbiota dysbiosis, despite increased IgM production, indicating IgA's non-redundant role in maintaining microbial balance.

bioRxiv · Oct 30, 2018Immunology