Author

D. Koot

University Medical Center Groningen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Floris FoijeriD· 1 shared H. Rudolf de BoeriD· 1 shared Lin ZhouiD· 1 shared Marcel A.T.M. van VugtiD· 1 shared Marsudi Siburian· 1 shared Petra L. BakkeriD· 1 shared René WardenaariD· 1 shared Ruifang Tian· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Floris FoijerORCID

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1 paper

Recent·Most cited

p53 activity links chromosomal instability to pro-migratory extracellular vesicles

Ruifang Tian, Siqi Zheng, Lin Zhou, Marsudi Siburian, René Wardenaar, H. Rudolf de Boer, Petra L. Bakker, D. Koot, Xiao Ling, Marcel A.T.M. van Vugt, Floris Foijer

The paper shows that chromosomal instability (CIN) leads to distinct p21-expressing cell populations with different cell-cycle recovery and extracellular vesicle (EV) properties, resulting in increased migration.

bioRxiv · Oct 13, 2026 · PreprintCancer Biology