Author

D. L. George

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1 Assay:metabolomics· 1 Organism:mouse· 1

Frequent Co-Authors

C.-P. Kung· 1 shared J. A. Baur· 1 shared J. I.-J. Leu· 1 shared J. V. Lee· 1 shared K. E. Wellen· 1 shared K. Gnanapradeepan· 1 shared M. E. Murphy· 1 shared M. Good· 1 shared

Activity by Year

2020-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

C.-P. Kung

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1 paper

Recent·Most cited

Increased mTOR activity and metabolic efficiency in mouse and human cells containing the African-centric tumor-predisposing p53 variant Pro47Ser

K. Gnanapradeepan, S. Basu, T. Barnoud, J. I.-J. Leu, M. Good, J. V. Lee, W. J. Quinn, C.-P. Kung, R. S. Ahima, J. A. Baur, K. E. Wellen, Q. Liu, Z. T. Schug, D. L. George, M. E. Murphy

This study shows that the p53 variant Pro47Ser increases mTOR activity and metabolic efficiency in mouse and human cells through altered redox regulation of Rheb.

bioRxiv · Feb 14, 2020Cancer Biology