Multi-level force-dependent allosteric enhancement of αE-catenin binding to F-actin by vinculin
N. A. Bax, A. Wang, D. L. Huang, S. Pokutta, W. I. Weis, A. R. Dunn
This study investigates how multiple cadherin-catenin complexes interact with F-actin under force and how vinculin enhances this interaction, revealing cooperative mechanisms that strengthen cell-cell junctions.
bioRxiv · May 7, 2022Biophysics