Author

S. Pokutta

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biophysics· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Approach:biophysical modeling· 1 Assay:cryo-EM· 1 Research Focus:development & morphogenesis· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

W. I. Weis· 3 shared A. P. Hinck· 1 shared A. R. Dunn· 1 shared A. V. Kwiatkowski· 1 shared A. Wang· 1 shared D. Hanein· 1 shared D. L. Huang· 1 shared I. W. Dale· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersBiophysics

W. I. Weis

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Multi-level force-dependent allosteric enhancement of αE-catenin binding to F-actin by vinculin

N. A. Bax, A. Wang, D. L. Huang, S. Pokutta, W. I. Weis, A. R. Dunn

This study investigates how multiple cadherin-catenin complexes interact with F-actin under force and how vinculin enhances this interaction, revealing cooperative mechanisms that strengthen cell-cell junctions.

bioRxiv · May 7, 2022Biophysics

Distinct autoinhibitory mechanisms regulate vinculin binding by alpha-T-catenin and alpha-E-catenin

J. A. Heier, S. Pokutta, I. W. Dale, S. K. Kim, A. P. Hinck, W. I. Weis, A. V. Kwiatkowski

This study identifies distinct autoinhibitory mechanisms in T-catenin and E-catenin regulating vinculin binding, showing that T-catenin's N-terminus maintains M-region autoinhibition.

bioRxiv · Oct 25, 2020 · PreprintBiochemistry

Structural basis of αE-catenin-F-actin catch bond behavior

X.-P. Xu, S. Pokutta, M. Torres, M. F. Swift, D. Hanein, N. Volkmann, W. I. Weis

The paper describes the cryo-EM structure of E-catenin's actin-binding domain and explains how mechanical force affects its binding to F-actin, revealing the mechanism of catch bond behavior.

eLife · Sep 11, 2020Peer-reviewedBiophysics