Author

D. L. Valentine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:bacteria (other)· 4 Research Focus:gene regulatory network inference· 4 Research Focus:cell type annotation· 3 Research Focus:chromatin & epigenetic regulation· 3 Assay:metagenomics· 3 Approach:statistical model· 2 Assay:whole-genome sequencing· 2

Frequent Co-Authors

B. G. Paul· 4 shared V. Kivenson· 3 shared A. Vallota-Eastman· 2 shared E. C. Arrington· 2 shared M. A. O'Malley· 2 shared A. Ganesh· 1 shared A. R. Eisenberg· 1 shared C. Bui· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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4 shared papersMicrobiology

B. G. Paul

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Targeted hypermutation of putative antigen sensors in multicellular bacteria

H. Dore, A. R. Eisenberg, E. N. Junkins, A. Ganesh, O. X. Cordero, B. G. Paul, D. L. Valentine, M. A. O'Malley, E. G. Wilbanks

The paper shows multicellular bacteria use DGRs to diversify antigen sensors, enhancing adaptive immunity and supporting the evolution of multicellularity.

bioRxiv · Sep 22, 2023 · PreprintMicrobiology

Pontiella agarivorans sp. nov., a novel marine anaerobic bacterium capable of degrading macroalgal polysaccharides and fixing nitrogen

N. Liu, V. Kivenson, X. Peng, Z. Cui, T. Lankiewicz, K. M. Gosselin, M. A. O'Malley, D. L. Valentine

bioRxiv · Jun 9, 2023 · PreprintMicrobiology

Bacillus subtilis engineered for aerospace medicine: a platform for off-planet production of pharmaceutical peptides

A. Vallota-Eastman, C. Bui, P. P. Williams, D. L. Valentine, D. Loftus, L. J. Rothschild

This paper engineers Bacillus subtilis to produce pharmaceutical peptides for space missions, demonstrating feasible on-site production of teriparatide and filgrastim in 24 hours.

bioRxiv · Feb 22, 2023 · PreprintPharmacology & Toxicology

Methylated Cycloalkanes Fuel a Novel Genera in the Porticoccaceae Family and Inform Substrate Affinity for a Unique Copper Membrane Monooxygenase

E. C. Arrington, J. Tarn, H. Kittner, V. Kivenson, R. M. Liu, D. L. Valentine

This study investigates microbial metabolism of methylcycloalkanes in the Gulf of Mexico, identifying a novel bacterial genus and a unique copper membrane monooxygenase involved in their degradation.

bioRxiv · Nov 7, 2022 · PreprintMicrobiology

An ecological basis for dual genetic code expansion in marine deltaproteobacteria

V. Kivenson, B. G. Paul, D. L. Valentine

The paper identifies genetic code expansion in marine Deltaproteobacteria, showing it enhances metabolic functions and ecological success in diverse environments.

Frontiers in Microbiology · Jul 14, 2021Peer-reviewedMicrobiology

Role of Diversity-Generating Retroelements for Regulatory Pathway Tuning in Cyanobacteria

A. Vallota-Eastman, E. C. Arrington, S. Meeken, S. Roux, S. Rosen, K. Dasari, J. F. Miller, D. L. Valentine, B. G. Paul

This study identifies DGRs in cyanobacteria and shows they diversify regulatory proteins involved in signal response, particularly in colonial and filamentous strains.

bioRxiv · May 26, 2020Microbiology

Unusual metabolism and hypervariation in the genome of a Gracilibacteria (BD1-5) from an oil degrading community

C. M. K. Sieber, B. G. Paul, C. J. Castelle, P. Hu, S. G. Tringe, D. L. Valentine, G. L. Andersen, J. F. Banfield

The paper reports the first closed genome of a Gracilibacteria from an oil-degrading community, revealing unusual metabolism and a hypervariable repeat region with potential functional significance.

bioRxiv · Apr 1, 2019Microbiology