Author

B. G. Paul

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6 Ecology· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 5 Approach:experimental assay· 4 Research Focus:gene regulatory network inference· 4 Assay:metagenomics· 4 Approach:statistical model· 4 Organism:bacteria (other)· 2 Research Focus:cell type annotation· 2 Organism:C. elegans· 1

Frequent Co-Authors

D. L. Valentine· 4 shared A. Ganesh· 2 shared M. A. O'Malley· 2 shared S. Roux· 2 shared A. Giblin· 1 shared A. R. Eisenberg· 1 shared A. Vallota-Eastman· 1 shared B. Mortazavi· 1 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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4 shared papersMicrobiology

D. L. Valentine

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Structural Requirements for Reverse Transcription by a Diversity-generating Retroelement

S. Handa, T. Biswas, J. Chakraborty, G. Ghosh, B. G. Paul, P. Ghosh

This study identifies how surrounding RNA structures facilitate reverse transcription in DGRs by positioning an RNA homoduplex for cis-priming and regulating mutagenesis.

bioRxiv · Oct 23, 2023Microbiology

Targeted hypermutation of putative antigen sensors in multicellular bacteria

H. Dore, A. R. Eisenberg, E. N. Junkins, A. Ganesh, O. X. Cordero, B. G. Paul, D. L. Valentine, M. A. O'Malley, E. G. Wilbanks

The paper shows multicellular bacteria use DGRs to diversify antigen sensors, enhancing adaptive immunity and supporting the evolution of multicellularity.

bioRxiv · Sep 22, 2023 · PreprintMicrobiology

Diversity at single nucleotide to pangenome scales among sulfur cycling bacteria in salt marshes

S. Perez Castro, E. L. Peredo, O. Mason, J. H. Vineis, J. L. Bowen, B. Mortazavi, A. Ganesh, S. E. Ruff, B. G. Paul, A. Giblin, Z. Cardon

This study characterizes sulfur-cycling microbial diversity in salt marshes using metagenomics, revealing genomic variation across sites and plant species.

bioRxiv · Jun 8, 2023 · PreprintEcology

An ecological basis for dual genetic code expansion in marine deltaproteobacteria

V. Kivenson, B. G. Paul, D. L. Valentine

The paper identifies genetic code expansion in marine Deltaproteobacteria, showing it enhances metabolic functions and ecological success in diverse environments.

Frontiers in Microbiology · Jul 14, 2021Peer-reviewedMicrobiology

Ecology and molecular targets of hypermutation in the global microbiome.

S. Roux, B. G. Paul, S. C. Bagby, M. A. Allen, G. Attwood, R. Cavicchioli, L. Chistoserdova, S. Hallam, M. E. Hernandez, M. Hess, W.-T. Liu, M. A. O'Malley, X. Peng, V. I. Rich, S. Saleska, E. A. Eloe-Fadrosh

The paper analyzes metagenome-derived DGRs to show their evolutionary origin, mutation bias, ecological niches, and role in microbial community dynamics.

Nature Communications · May 24, 2021Peer-reviewedMicrobiology

Role of Diversity-Generating Retroelements for Regulatory Pathway Tuning in Cyanobacteria

A. Vallota-Eastman, E. C. Arrington, S. Meeken, S. Roux, S. Rosen, K. Dasari, J. F. Miller, D. L. Valentine, B. G. Paul

This study identifies DGRs in cyanobacteria and shows they diversify regulatory proteins involved in signal response, particularly in colonial and filamentous strains.

bioRxiv · May 26, 2020Microbiology

Unusual metabolism and hypervariation in the genome of a Gracilibacteria (BD1-5) from an oil degrading community

C. M. K. Sieber, B. G. Paul, C. J. Castelle, P. Hu, S. G. Tringe, D. L. Valentine, G. L. Andersen, J. F. Banfield

The paper reports the first closed genome of a Gracilibacteria from an oil-degrading community, revealing unusual metabolism and a hypervariable repeat region with potential functional significance.

bioRxiv · Apr 1, 2019Microbiology