Author

L. J. Rothschild

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Microbiology· 1 Pharmacology & Toxicology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Organism:bacteria (other)· 1 Organism:C. elegans· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Carbajal· 1 shared A. J. Maheshwari· 1 shared A. Vallota-Eastman· 1 shared C. Bui· 1 shared C. Calvet· 1 shared D. F. Jarosz· 1 shared D. Kunin· 1 shared D. L. Valentine· 1 shared

Activity by Year

2015-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperEvolutionary Biology

A. Carbajal

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Author profile →

4 papers

Recent·Most cited

Bacillus subtilis engineered for aerospace medicine: a platform for off-planet production of pharmaceutical peptides

A. Vallota-Eastman, C. Bui, P. P. Williams, D. L. Valentine, D. Loftus, L. J. Rothschild

This paper engineers Bacillus subtilis to produce pharmaceutical peptides for space missions, demonstrating feasible on-site production of teriparatide and filgrastim in 24 hours.

bioRxiv · Feb 22, 2023 · PreprintPharmacology & Toxicology

Assessing the intrageneric environmental boundaries of the extremophilic cyanobacterium Chroococcidiopsis (Pleurocapsales) and its implications for space exploration

J. Cumbers, L. J. Rothschild

This study characterizes the environmental tolerance of Chroococcidiopsis strains, identifying two UV-resistant isolates with potential applications for space exploration.

bioRxiv · Aug 9, 2022 · PreprintMicrobiology

The hunt for ancient prions: Archaeal prion-like domains form amyloids and substitute for yeast prion domains

T. Zajkowski, M. D. Lee, S. S. Mondal, A. Carbajal, R. Dec, P. D. Brennock, R. W. Piast, J. E. Snyder, N. B. Bense, W. Dzwolak, D. F. Jarosz, L. J. Rothschild

This paper identifies prion-like domains in Archaea that form amyloids and transmit non-Mendelian inheritance, suggesting prions existed in the last universal common ancestor.

bioRxiv · Jul 20, 2020 · PreprintEvolutionary Biology

CRISPR/Cas9-Assisted Transformation-Efficient Reaction (CRATER), a novel method for selective transformation

L. J. Rothschild, D. T. Greenberg, J. R. Takahashi, K. A. Thompson, A. J. Maheshwari, R. E. Kent, G. McCutcheon, J. D. Shih, C. Calvet, T. D. Devlin, T. Ju, D. Kunin, E. Lieberman, T. Nguyen, F. G. Tran, , K. Fujishima

The paper introduces CRATER, a CRISPR/Cas9-based method that improves plasmid transformation efficiency by selectively cleaving unwanted byproducts, increasing efficiency from 20% to 97%.

bioRxiv · Sep 27, 2015 · PreprintSynthetic Biology