Author

D. Lauffenburger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. C. Belkina· 1 shared A. F. Ogunsola· 1 shared A. Fasano· 1 shared A. G. Edlow· 1 shared A. Kaimal· 1 shared A. Olson· 1 shared A. Starchenko· 1 shared C. Atyeo· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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1 shared paperImmunology

A. C. Belkina

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3 papers

Recent·Most cited

Host genetic background is a barrier to broadly effective vaccine protection: Relevance to BCG and Mycobacterium tuberculosis Infection

R. Lai, D. Gong, T. Williams, A. F. Ogunsola, K. Cavallo, C. L. Arlehamn, G. Beamer, M. Ferris, C. M. Sassetti, D. Lauffenburger, S. Behar

This study shows that host genetic background affects BCG vaccine efficacy against tuberculosis, with diverse immune responses in genetically varied mice.

bioRxiv · Sep 19, 2022 · PreprintImmunology

Sexually dimorphic placental responses to maternal SARS-CoV-2 infection

E. A. Bordt, L. L. Shook, C. Atyeo, K. M. Pullen, R. M. De Guzman, M.-C. Meinsohn, M. Chauvin, S. Fischinger, L. J. Yockey, K. James, R. Lima, L. M. Yonker, A. Fasano, S. Brigida, L. M. Bebell, , A. G. Edlow

The paper investigates sex differences in placental responses to maternal SARS-CoV-2 infection, finding sex-specific changes in interferon genes, Fc-receptor expression, and antibody transfer.

bioRxiv · Mar 29, 2021 · PreprintImmunology

Multivariate Computational Analysis of Gamma Delta T cell Inhibitory Receptor Signatures Reveals the Divergence of Healthy and ART-Suppressed HIV+ Aging

A. C. Belkina, A. Starchenko, K. Drake, E. Proctor, R. Pihl, A. Olson, D. Lauffenburger, N. Lin, J. E. Snyder-Cappione

This study identifies divergent inflammatory signatures in ART-suppressed HIV+ individuals compared to uninfected controls using multivariate analysis of immune receptor and plasma marker data.

bioRxiv · Nov 20, 2018Immunology