Author

D. Gong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Immunology· 2 Biochemistry· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Organism:human· 5 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Y. Yang· 2 shared A. Drelich· 1 shared A. F. Ogunsola· 1 shared A. Gaitas· 1 shared B. Gong· 1 shared C. Fernandez-del Castillo· 1 shared C. L. Arlehamn· 1 shared C. M. Sassetti· 1 shared

Activity by Year

2017-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersImmunology

Y. Yang

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Therapy-associated remodeling of pancreatic cancer revealed by single-cell spatial transcriptomics and optimal transport analysis

C. Shiau, J. Cao, M. T. Gregory, D. Gong, X. Yin, J.-W. Cho, P. L. Wang, J. Su, S. Wang, J. W. Reeves, T. K. Kim, Y. Kim, J. A. Guo, N. A. Lester, N. Schurman, , W. L. Hwang

This study uses single-cell spatial transcriptomics and optimal transport analysis to reveal therapy-induced changes in pancreatic cancer microenvironment interactions.

bioRxiv · Jun 28, 2023 · PreprintCancer Biology

Host genetic background is a barrier to broadly effective vaccine protection: Relevance to BCG and Mycobacterium tuberculosis Infection

R. Lai, D. Gong, T. Williams, A. F. Ogunsola, K. Cavallo, C. L. Arlehamn, G. Beamer, M. Ferris, C. M. Sassetti, D. Lauffenburger, S. Behar

This study shows that host genetic background affects BCG vaccine efficacy against tuberculosis, with diverse immune responses in genetically varied mice.

bioRxiv · Sep 19, 2022 · PreprintImmunology

Type 17 Follicular Helper T (Tfh17) Cells are Superior for Memory Maintenance

X. Gao, K. Luo, D. Wang, Y. Wei, Y. Yao, J. Deng, Y. Yang, Q. Zeng, X. Dong, L. Xiong, D. Gong, L. Lin, K. Pohl, S. Liu, Y. Liu, , D. Yu

This study shows that Tfh17 cells are more effective than Tfh1 and Tfh2 cells in maintaining memory responses after vaccination.

bioRxiv · Jul 31, 2022Immunology

Molecular basis for allosteric regulation of the type 2 ryanodine receptor channel gating by key modulators

X. Chi, D. Gong, K. Ren, G. Zhou, G. Huang, J. Lei, Q. Zhou, N. Yan

The paper reports cryo-EM structures of RyR2 bound to modulators, revealing how Ca2+ and other molecules regulate channel gating and provide insights into cardiac disorder mechanisms.

bioRxiv · Jul 19, 2019Biochemistry

Preclinical Study: Sunitinib-suppressed MiR-452-5p Facilitates Renal Cancer Cell Invasion and Metastasis Through Modulating SMAD4/SMAD7/EMT Signals

W. Zhai, S. Li, J. Zhang, Y. Chen, J. Ma, W. Kong, D. Gong, J. Zheng, W. Xue, Y. Xu

This study identifies miR-452-5p as a key regulator of renal cancer metastasis, showing its upregulation and role in promoting invasion through SMAD4/SMAD7/EMT signaling.

bioRxiv · Mar 22, 2018Cancer Biology

High-throughput fitness profiling of Zika virus E protein reveals different roles for N-linked glycosylation during infection of mammalian and mosquito cells

D. Gong, T.-h. Zhang, D. Zhao, Y. Du, T. J. Chapa, Y. Shi, L. Wang, D. Contreras, G. Zeng, P.-y. Shi, T.-T. Wu, V. Arumugaswami, R. Sun

This study identifies the role of N-linked glycosylation in ZIKV E protein function across mosquito and human cells using a mutant library.

bioRxiv · Oct 8, 2017Microbiology

Exchange protein directly activated by cAMP plays a critical role in regulation of vascular fibrinolysis

X. He, A. Drelich, Q. Chang, D. Gong, Y. Zhou, Y. Qu, S. Yu, Y. Yang, J. Qian, Y. Qiu, S.-J. Tang, A. Gaitas, T. Ksiazek, Z. Xu, M. Wakamiya, , B. Gong

This study shows that EPAC1 promotes ANXA2 translocation to endothelial cell surfaces, enhancing plasminogen to plasmin conversion and fibrinolysis.

bioRxiv · Oct 1, 2017Cell Biology