Author

D. Lechardeur

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

D. Lipuma· 2 shared P. Arnoux· 2 shared V. Saillant· 2 shared A. Boussac· 1 shared B. Kerouault· 1 shared C. Guerin· 1 shared D. Rigaudeau· 1 shared E. Duchaud· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersMicrobiology

D. Lipuma

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

HssS activation by membrane heme defines a paradigm for 2-component system signaling in Staphylococcus aureus.

D. Lechardeur, V. Saillant, L. Morey, D. Lipuma, P. Boëton, P. Arnoux

This study identifies how heme binds to the HssS sensor in Staphylococcus aureus, triggering a signaling cascade that activates heme efflux to prevent toxicity.

bioRxiv · Nov 3, 2022 · PreprintMicrobiology

Two functionally distinct heme/iron transport systems are virulence determinants of the fish pathogen Flavobacterium psychrophilum

Y. Zhu, D. Lechardeur, J.-F. Bernardet, B. Kerouault, C. Guerin, D. Rigaudeau, P. Nicolas, E. Duchaud, T. Rochat

This study identifies two heme/iron transport systems in Flavobacterium psychrophilum that are essential for virulence and adaptation to iron conditions during infection.

bioRxiv · Apr 4, 2022Microbiology

A novel Enterococcus faecalis heme transport regulator (FhtR) is a heme sensor in the gastrointestinal tract.

V. Saillant, D. Lipuma, E. Ostyn, L. Joubert, A. Boussac, H. Guerin, G. Brandelet, P. Arnoux, D. Lechardeur

This paper identifies FhtR as a heme sensor in E. faecalis that regulates heme homeostasis by controlling an efflux pump and catalase expression in the gastrointestinal tract.

mBio · Feb 23, 2021Peer-reviewedMicrobiology