Cell BiologybioRxiv
Stress-induced phase separation of ERES components into Sec bodies precedes ER exit inhibition in mammalian cells.
W. van Leeuwen, D. M. D. Nguyen, R. Grond…·C. Rabouille
The paper shows stress-induced phase separation of ERES components into Sec bodies inhibits ER exit in mammalian cells, with Sec16A driving this process and its depletion from ERES causing functional inhibition.
DOI 10.1242/jcs.260294