Author

D. M. Mishler

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Evolutionary Biology· 1

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Organism:Arabidopsis· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

J. E. Barrick· 1 shared P. Geng· 1 shared S. P. Leonard· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperEvolutionary Biology

J. E. Barrick

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1 paper

Recent·Most cited

Synthetic genome defenses against selfish DNA elements stabilize engineered bacteria against evolutionary failure

P. Geng, S. P. Leonard, D. M. Mishler, J. E. Barrick

This paper develops a CRISPR-based system to silence transposons in bacteria, improving genome stability and reducing mutation rates in engineered cells.

bioRxiv · Sep 16, 2018Evolutionary Biology