Glioblastoma myeloid-derived suppressor cell subsets express differential macrophage migration inhibitory factor receptor profiles that can be targeted to reduce immune suppression
T. Alban, D. Bayik, B. Otvos, A. Rabljenovic, L. Leng, L. Jia-shiun, G. Roversi, A. Lauko, A. Momin, A. M. Mohammadi, D. M. Peereboom, M. S. Ahluwalia, K. Matsuda, K. Yun, R. Bucala, , J. Lathia
This study identifies differential MIF receptor expression in GBM MDSC subsets and shows targeting M-MDSCs with ibudilast reduces immune suppression.
bioRxiv · Dec 19, 2019Immunology