K. Yun

Involvement of ArlI, ArlJ, and CirA in Archaeal Type-IV Pilin-Mediated Motility Regulation

This study identifies ArlI, ArlJ, and CirA as regulators of pilin-mediated motility in Haloferax volcanii through genetic and expression analyses.

Optimized CART Cell Therapy for Metastatic Aggressive Thyroid Cancer

This paper develops a TSHR-targeted CART cell therapy for thyroid cancer and shows that combining it with MAPK inhibitors improves antitumor efficacy in dedifferentiated thyroid cancers.

Halofilins as Emerging Bactofilin Families of Archaeal Cell Shape Plasticity Orchestrators

This study identifies and characterizes two new families of archaeal bactofilins, HalA and HalB, showing their roles in shaping cell morphology and curvature in Haloferax volcanii.

The Identification of IL-4 as a Regulator of Chimeric Antigen Receptor T Cell Exhaustion

This study identifies IL-4 as a regulator of CART cell exhaustion and shows that IL-4 neutralization improves antitumor efficacy.

A prognostic matrix code defines functional glioblastoma phenotypes and niches.

This paper identifies a matrix code based on extracellular core matrix proteins that categorizes glioblastoma tumors into prognostic groups and predicts responses to PD1 blockade.

Sex-biased Yap1 oncogene function

This study shows that Yap1, an oncogene, has sex-biased functions in medulloblastoma progression and immune suppression, with greater impact in males.

Cropbox: a declarative crop modeling framework

Cropbox provides a declarative framework for crop modeling, enabling transparent and accessible model development through automated code generation from high-level specifications.

An integrative process-based model for biomass and yield estimation of hardneck garlic (Allium sativum)

The paper introduces an integrative process-based crop model for garlic to estimate biomass and yield under diverse environmental conditions and assess climate adaptation strategies.

Glioblastoma myeloid-derived suppressor cell subsets express differential macrophage migration inhibitory factor receptor profiles that can be targeted to reduce immune suppression

This study identifies differential MIF receptor expression in GBM MDSC subsets and shows targeting M-MDSCs with ibudilast reduces immune suppression.