Cbl and Cbl-b Ubiquitin Ligases are Essential for Intestinal Epithelial Stem Cell Maintenance
N. Zutshi, B. C. Mohapatra, P. Mondal, W. An, B. T. Goetz, S. Wang, S. Li, M. D. Storck, D. Mercer, A. R. Black, S. P. Thayer, J. Black, C. Lin, V. Band, H. Band
This study shows that Cbl and Cbl-b ubiquitin ligases are essential for intestinal epithelial stem cell maintenance by regulating the Akt-mTOR pathway.
bioRxiv · May 17, 2023Cell Biology