Author

P. Mondal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Cancer Biology· 2 Pharmacology & Toxicology· 2 Bioengineering· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 8 Research Focus:drug response / drug discovery· 4 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:mouse· 2 Organism:non-human primate· 2 Assay:behavioral assay· 1

Frequent Co-Authors

A. Bandyopadhyay· 1 shared A. Bhansali· 1 shared A. Choubey· 1 shared A. D. Bhowmik· 1 shared A. Dermenci· 1 shared A. Flick· 1 shared A. J. Lazenby· 1 shared A. K. Kar· 1 shared

Activity by Year

2019-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 7 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperPharmacology & Toxicology

A. Bandyopadhyay

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Structural basis for CCR6 modulation by allosteric antagonists

D. J. Wasilko, B. S. Gerstenberger, K. A. Farley, W. Li, J. Alley, M. E. Schnute, R. J. Unwalla, J. Victorino, K. K. Crouse, R. Ding, P. V. Sahasrabudhe, F. Vincent, R. K. Frisbie, A. Dermenci, A. Flick, , H. Wu

This paper presents two inactive CCR6 structures bound to allosteric antagonists, revealing structural insights into CCR6 inhibition and its implications for drug discovery.

bioRxiv · Apr 5, 2024Biochemistry

A whole-genome CRISPR screen identifies the spindle accessory checkpoint as a locus of nab-paclitaxel resistance in pancreatic cancer cells

P. Mondal, G. Alyateem, A. V. Mitchell, M. M. Gottesman

bioRxiv · Feb 15, 2024 · PreprintCancer Biology

Development of non-sedating antischistosomal benzodiazepines

M. Y. Mian, D. Sharmin, P. Mondal, J. B. Belayet, M. M. Hossain, P. McCusker, K. T. Ryan, A. Y. Fedorov, H. A. Green, S. S. Ericksen, M. Zamanian, V. V. N. Phani Babu Tiruveedhula, J. M. Cook, J. D. Chan

This paper develops non-sedating antischistosomal benzodiazepines by modifying meclonazepam's structure, identifying compounds effective in vivo with reduced sedation.

bioRxiv · Jan 26, 2024 · PreprintPharmacology & Toxicology

Molecular basis of VEGFR1 autoinhibition at the plasma membrane

M. P. Chakraborty, D. Das, P. Mondal, P. Kaul, S. Bhattacharyya, P. K. Das, R. Das

This study identifies a mechanism by which VEGFR1 remains constitutively inactive through juxtamembrane inhibition and phosphatase activity, explaining its differential regulation compared to VEGFR2.

bioRxiv · Jun 8, 2023Biochemistry

Cbl and Cbl-b Ubiquitin Ligases are Essential for Intestinal Epithelial Stem Cell Maintenance

N. Zutshi, B. C. Mohapatra, P. Mondal, W. An, B. T. Goetz, S. Wang, S. Li, M. D. Storck, D. Mercer, A. R. Black, S. P. Thayer, J. Black, C. Lin, V. Band, H. Band

This study shows that Cbl and Cbl-b ubiquitin ligases are essential for intestinal epithelial stem cell maintenance by regulating the Akt-mTOR pathway.

bioRxiv · May 17, 2023Cell Biology

Arsenic induced alteration of neuroregulatory gene expression in Macrobrachium lamarrei: a neurotoxicological approach to grooming behaviour

C. Munshi, A. Mukhuty, A. Bandyopadhyay, A. D. Bhowmik, P. Mondal, P. Shaw, S. Bhattacharya

This study examines how arsenic trioxide affects neuroregulatory gene expression and induces autism-like behaviors in the freshwater prawn Macrobrachium lamarrei.

bioRxiv · Aug 30, 2022 · PreprintPharmacology & Toxicology

Induction of pancreatic neoplasia in the KRAS/TP53 Oncopig

P. Mondal, N. Patel, K. Bailey, S. Aravind, M. A. Hollingsworth, A. J. Lazenby, M. A. Carlson

This study induces and characterizes pancreatic tumors in Oncopigs to create a large animal model of pancreatic cancer with molecular features similar to human disease.

bioRxiv · May 29, 2020Cancer Biology

Hyperinsulinemia promotes HMGB1 release leading to inflammation induced systemic insulin resistance: An interplay between pancreatic beta-cell and peripheral organs

A. Choubey, A. K. Kar, K. Girdhar, T. Chattopadhyay, S. Dogra, S. Kushwaha, B. Medhi, A. Bhansali, C. K. Mantri, U. K. Seetharam, D. Ghosh, P. Mondal

This study shows hyperinsulinemia promotes inflammation via HMGB1 and TLR4 signaling, leading to systemic insulin resistance, and demonstrates naltrexone's protective effects.

bioRxiv · Jul 17, 2019 · PreprintPhysiology

Repurposing protein degradation for optogenetic modulation of protein activities

P. Mondal, V. V. Krishnamurthy, S. R. Sharum, N. Haack, K. Zhang

This paper introduces GLIMPSe, a light-modulated protein stabilization system that controls protein levels in live cells without requiring target-specific engineering.

bioRxiv · Jun 23, 2019Bioengineering