Apolipoprotein A1 and high-density lipoprotein limit low-density lipoprotein transcytosis by binding scavenger receptor B1
K. Fung, T. W. W. Ho, Z. Xu, D. Neculai, C. Beauchemin, W. Lee, G. D. Fairn
This study shows that APOA1 and HDL reduce LDL transcytosis by competing with LDL for SR-B1 binding, thereby limiting atherosclerosis.
bioRxiv · Aug 8, 2022 · PreprintBiochemistry