Structural mechanism of regioselectivity in an unusual bacterial acyl-CoA dehydrogenase
J. M. Blake-Hedges, J. Henrique Pereira, P. Cruz-Morales, M. G. Thompson, J. F. Barajas, J. Chen, R. N. Krishna, L. J. G. Chan, D. Nimlos, C. Alonso-Martinez, E. Baidoo, Y. Chen, J. W. Gin, L. Katz, C. J. Petzold, , J. D. Keasling
This paper investigates the structural mechanism of regioselectivity in a bacterial acyl-CoA dehydrogenase, identifying key residues and structural features responsible for its unique substrate specificity.
bioRxiv · Oct 22, 2019Biochemistry