Author

J. W. Gin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Biochemistry· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Assay:proteomics· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

C. J. Petzold· 5 shared Y. Chen· 4 shared J. D. Keasling· 3 shared P. D. Adams· 3 shared E. Baidoo· 2 shared J. F. Barajas· 2 shared J. M. Blake-Hedges· 2 shared M. G. Thompson· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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5 shared papersMicrobiology

C. J. Petzold

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5 papers

Recent·Most cited

Bottlenecks in the Implementation of Genome Scale Metabolic Model Based Designs for Bioproduction from Aromatic Carbon Sources

D. Banerjee, J. Menasalvas, Y. Chen, J. W. Gin, E. E. Baidoo, C. J. Petzold, T. Eng, A. Mukhopadhyay

This study identifies fumarate hydratase activity as a bottleneck in a genome-scale metabolic model design for bioproduction from para-coumarate, requiring optimization for growth and product formation.

bioRxiv · Mar 15, 2024Microbiology

Genetically refactored Agrobacterium-mediated transformation

M. Thompson, L. D. Kirkpatrick, G. M. Geiselman, L. M. Waldburger, A. N. Pearson, M. Szarzanowicz, K. M. Vuu, K. Markel, N. F. Hummel, D. D. Suazo, C. Tahmin, R. Cui, S. Liu, J. Cevallos, H. Pannu, , P. M. Shih

This paper refactors the Agrobacterium tumor-inducing plasmid into a minimal set of genes for plant and fungal transformation, demonstrating a bottom-up engineering approach.

bioRxiv · Oct 13, 2023 · PreprintMicrobiology

Simultaneous carbon catabolite repression governs sugar and aromatic co-utilization in Pseudomonas putida M2

S. Shrestha, D. Awasthi, Y. Chen, J. W. Gin, C. J. Petzold, P. D. Adams, B. A. Simmons, S. Singer

This study investigates carbon catabolite repression in Pseudomonas putida M2 during simultaneous sugar and aromatic co-utilization, revealing simultaneous repression by sugars and aromatics and the role of crc and small RNAs.

bioRxiv · May 23, 2023 · PreprintMicrobiology

Structural mechanism of regioselectivity in an unusual bacterial acyl-CoA dehydrogenase

J. M. Blake-Hedges, J. Henrique Pereira, P. Cruz-Morales, M. G. Thompson, J. F. Barajas, J. Chen, R. N. Krishna, L. J. G. Chan, D. Nimlos, C. Alonso-Martinez, E. Baidoo, Y. Chen, J. W. Gin, L. Katz, C. J. Petzold, , J. D. Keasling

This paper investigates the structural mechanism of regioselectivity in a bacterial acyl-CoA dehydrogenase, identifying key residues and structural features responsible for its unique substrate specificity.

bioRxiv · Oct 22, 2019Biochemistry

Massively parallel fitness profiling reveals multiple novel enzymes in Pseudomonas putida lysine metabolism

M. G. Thompson, J. M. Blake-Hedges, P. Cruz-Morales, J. F. Barajas, S. C. Curran, C. B. Eiben, N. C. Harris, V. T. Benites, J. W. Gin, W. A. Sharpless, F. F. Twigg, W. Skyrud, R. N. Krishna, J. H. Pereira, E. Baidoo, , J. D. Keasling

This paper uses RB-TnSeq to identify novel enzymes in Pseudomonas putida lysine metabolism, revealing new biochemical pathways and functions for DUF1338 proteins.

bioRxiv · Mar 18, 2019Microbiology