A time and single-cell resolved model of hematopoiesis
I. Kucinski, J. Campos, M. Barile, F. Severi, N. Bohin, P. N. Moreira, L. Allen, H. Lawson, M. L. R. Haltalli, S. J. Kinston, D. O'Carroll, K. R. Kranc, B. Göttgens
The paper builds a real-time, quantitative model of hematopoiesis using time-series single-cell RNA-Seq and persistent labeling, revealing lineage-specific self-renewal and differentiation properties.
bioRxiv · Sep 7, 2022 · PreprintCell Biology