Author

H. Lawson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

K. Kranc· 3 shared J. Campos· 2 shared A. J. Finch· 1 shared A. J. Simpson· 1 shared A. M. Magee· 1 shared A. Rio-Machin· 1 shared A. Rostron· 1 shared A. S. Mirchandani· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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Curved chords = mutual co-authorship

3 shared papersCancer Biology

K. Kranc

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

SCD inhibition eradicates AML displaying high de novo fatty acid desaturation and synergizes with chemotherapy

V. Dembitz, H. Lawson, R. Burt, C. Philippe, S. C. James, S. Atkinson, J. Durko, L. M. Wang, J. Campos, A. M. Magee, K. Woodley, M. J. Austin, A. Rio-Machin, P. Casado-Izquierdo, F. Bewicke-Copley, , P. Gallipoli

SCD inhibition induces AML cell death and synergizes with chemotherapy to prolong survival in murine AML models.

bioRxiv · Aug 2, 2023Cancer Biology

A time and single-cell resolved model of hematopoiesis

I. Kucinski, J. Campos, M. Barile, F. Severi, N. Bohin, P. N. Moreira, L. Allen, H. Lawson, M. L. R. Haltalli, S. J. Kinston, D. O'Carroll, K. R. Kranc, B. Göttgens

The paper builds a real-time, quantitative model of hematopoiesis using time-series single-cell RNA-Seq and persistent labeling, revealing lineage-specific self-renewal and differentiation properties.

bioRxiv · Sep 7, 2022 · PreprintCell Biology

Hypoxia shapes the immune landscape in lung injury promoting inflammation persistence

A. S. Mirchandani, S. J. Jenkins, C. C. Bain, H. Lawson, P. Coelho, F. Murphy, D. Griffith, A. Zhang, M. A. Sanchez-Garcia, L. Reyes, T. Morrison, S. Arienti, P. Sadiku, E. Watts, R. Dickinson, , S. Walmsley

This study shows hypoxia suppresses type I interferon signaling in ALI, leading to monocytopenia and unchecked inflammation, which can be mitigated by CSF1 administration.

bioRxiv · Mar 11, 2022 · PreprintCell Biology

The RNA m6A binding protein YTHDF2 promotes the B cell to plasma cell transition.

D. Turner, A. Saveliev, F. Salerno, L. S. Matheson, M. Screen, H. Lawson, D. Wotherspoon, K. Kranc, M. Turner

The paper identifies YTHDF2 as an m6A binding protein that promotes B cell to plasma cell transition in vitro and in chimeric mice.

bioRxiv · Jul 21, 2021 · PreprintImmunology