Systems-wide analysis of glycoprotein conformational changes by limited deglycosylation assay
S. N. Mule, L. Rosa-Fernandes, J. V. P. Coutinho, V. D. M. Gomes, J. Macedo-da-Silva, V. F. Santiago, D. O. Quina, G. S. de Oliveira, M. Thaysen-Andersen, M. R. Larsen, L. Labriola, G. Palmisano
The paper introduces a new method called LDA to analyze glycoprotein conformational changes on a systems-wide scale and demonstrates its application in detecting structural changes under ER stress.
bioRxiv · Jun 4, 2021Biochemistry