ATE1 activates ER-stress and UPR pathways in glioblastoma
J. Macedo-da-Silva, S. M. Oba-Shinjo, L. Rosa-Fernandes, R. d. S. Soares, A. M. Lerario, I. F. Moretti, T. d. S. Laurentino, R. C. Cintra, S. K. N. Marie, G. Palmisano
This study investigates the role of ATE1-mediated N-terminal arginylation in glioblastoma, finding it activates ER-stress and UPR pathways, promotes autophagy, and supports tumor growth.
bioRxiv · Sep 25, 2023 · PreprintCancer Biology