Inhibiting a mRNA motif binding protein that mediates TGF-β1 upregulation of translation attenuates pulmonary fibrosis in mice
W. Chen, D. Pilling, R. H. Gomer
The paper identifies an mRNA motif regulated by TGF-β1 that enhances translation of NEU3, and shows that inhibiting the binding protein DDX3 reduces pulmonary fibrosis in mice.
bioRxiv · Oct 23, 2022 · PreprintImmunology