D. Popovic

Human intestinal organoids with an autologoustissue-resident immune compartment

This study develops human intestinal immuno-organoids (IIOs) that integrate tissue-resident immune cells, enabling the study of intestinal inflammation and immune responses in disease contexts.

Ancient DNA reveals interstadials as a driver of the common vole population dynamics during the last glacial period

This study uses ancient DNA to show that interstadial periods, not the Last Glacial Maximum, were the main driver of common vole population dynamics during the last glacial period.

Reconstructing cell interactions and state trajectories in pancreatic cancer stromal tumoroids

This study develops a stromal tumoroid model of pancreatic cancer to investigate cell interactions and state changes, identifying key factors like SDC1 and PPARG that influence cancer cell behavior and therapy response.

Co-translational targeting of transcripts to endosomes

The paper identifies mRNAs that associate with early endosomes and shows that the coding region of EEA1 mRNA is sufficient for endosomal localization.

Locally-adapted Mimulus ecotypes differentially impact rhizosphere bacterial and archaeal communities in an environment-dependent manner

This study shows that locally adapted Mimulus ecotypes influence rhizosphere microbial communities, but environmental factors have a stronger impact than host genetics.

Mechanisms of a locally adaptive shift in allocation among growth, reproduction, and herbivore resistance in Mimulus guttatus

The paper investigates the genetic and physiological mechanisms underlying a locally adaptive shift in resource allocation between growth, reproduction, and herbivore resistance in Mimulus guttatus.

Oceanic salt spray and herbivore pressure contribute to local adaptation of coastal perennial and inland annual ecotypes of the Seep Monkeyflower (Mimulus guttatus)

This study shows that salt spray and herbivory, not soil water availability, drive local adaptation in coastal ecotypes of Mimulus guttatus, while inland adaptation is primarily influenced by soil water availability.

Human mediated dispersal of cats in the Neolithic Central Europe

The paper investigates mtDNA of Holocene Felis remains in Central Europe, finding an unexpectedly early presence of Near Eastern wildcat haplotypes, suggesting early human-mediated dispersal of cats during the Neolithic.