T. Yamaguchi

The interplay between peptides and RNA is critical for protoribosome compartmentalization and stability

This paper investigates the role of ribosomal peptides in protoribosome compartmentalization and stability, showing that RNA-protein interactions protect RNA from degradation and influence structural flexibility.

Heart generation via blastocyst complementation in Mesp1/2-deficient mice

This study generates functional adult hearts in Mesp1/2-deficient mice using blastocyst complementation with pluripotent stem cells, showing successful derivation of all cardiovascular lineages from exogenous cells.

Reconstructing cell interactions and state trajectories in pancreatic cancer stromal tumoroids

This study develops a stromal tumoroid model of pancreatic cancer to investigate cell interactions and state changes, identifying key factors like SDC1 and PPARG that influence cancer cell behavior and therapy response.

Genetically-linked simultaneous overexpression of multiple herbicide-metabolizing genes for broad-spectrum resistance in an agricultural weed Echinochloa phyllopogon

The paper identifies genetically linked overexpression of multiple herbicide-metabolizing genes in E. phyllopogon, enhancing and broadening metabolic resistance to multiple herbicides.

Ambiguous Body Ownership Experience Caused by Feeling-judgement Conflict: Evidence from Subjective Measurement in Rubber Hand Illusion using Integrated Information Theory

This study uses integrated information theory to explain ambiguous body ownership in rubber hand illusions, finding that subjective experience correlates with {Phi} values.

Empirical estimation of marine phytoplankton assemblages in coastal and offshore areas using an in situ multi-wavelength excitation fluorometer

The paper develops a method using a multi-wavelength fluorometer to estimate marine phytoplankton assemblages and finds that five taxonomic groups are well-estimated, with spatial and seasonal variations observed.

Expression of Spred2 in the urothelial tumorigenesis of the urinary bladder

The paper investigates Spred2 expression in urothelial tumors and finds it negatively correlates with ERK activation and Ki67 index in non-invasive papillary carcinoma.

Genetic characterization of Streptococcus pyogenes emm 89 strains isolated in Japan from 2011 to 2019

The paper characterizes emm89 Streptococcus pyogenes strains from Japan, finding most belong to clade 3 and carry STSS-associated genes and SNPs.

Isolation of an archaeon at the prokaryote-eukaryote interface

The paper isolates an Asgard archaeon and proposes a symbiosis model for eukaryogenesis based on its morphology and metabolism.

The first functional characterization of ancient interleukin-15-like (IL-15L) reveals shared and distinct functions of the IL-2, -15 and -15L family cytokines

This study characterizes the functional roles of IL-15L in rainbow trout, revealing shared and distinct functions compared to IL-2 and IL-15, and provides insights into cytokine family evolution.

Generation of human hepatic progenitor cells with regenerative and metabolic capacities from primary hepatocytes

This study generates human hepatic progenitor cells from primary hepatocytes that can repopulate injured livers and redifferentiate into functional hepatocytes.

Isolation of lactic acid bacteria capable of reducing environmental alkyl and fatty acid hydroperoxides, and the effect of their oral administration on oxidative-stressed nematodes and rats

The paper isolates two lactic acid bacteria capable of reducing hydroperoxides and shows their ability to extend lifespan in nematodes and inhibit lipid peroxidation in rats.

Residual Structure of Unfolded Ubiquitin as Revealed by Hydrogen/Deuterium-Exchange 2D NMR

This study investigates the residual structure of unfolded ubiquitin using H/D-exchange 2D NMR, identifying protected amide groups that suggest partial native β-hairpin structure in the unfolded state.