Author

D. R. Tyson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

V. Quaranta· 3 shared L. A. Harris· 2 shared A. L. R. Lubbock· 1 shared C. F. Lopez· 1 shared D. A. Jacobson· 1 shared J. Brinkley· 1 shared N. Panchy· 1 shared P. E. Stauffer· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCancer Biology

V. Quaranta

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Author profile →

3 papers

Recent·Most cited

Purinergic Ca2+ signaling as a novel mechanism of drug tolerance in BRAF mutant melanoma

P. E. Stauffer, J. Brinkley, D. A. Jacobson, V. Quaranta, D. R. Tyson

This study identifies purinergic Ca2+ signaling via P2X7 receptors as a mechanism enabling drug tolerance in BRAF-mutant melanoma, with implications for overcoming treatment resistance.

bioRxiv · Nov 3, 2023Cancer Biology

Involvement of epithelial-mesenchymal transition genes in small cell lung cancer phenotypic plasticity

S. M. Groves, N. Panchy, D. R. Tyson, L. A. Harris, V. Quaranta, T. Hong

This study examines the relationship between epithelial-mesenchymal transition (EMT) and SCLC subtype plasticity using transcriptome data from mouse models and human samples.

bioRxiv · Sep 9, 2022Cancer Biology

Thunor: Visualization and Analysis of High-Throughput Dose-response Datasets

A. L. R. Lubbock, L. A. Harris, V. Quaranta, D. R. Tyson, C. F. Lopez

Thunor is an open-source platform for managing, analyzing, and visualizing dose-response datasets, providing interactive tools for drug response studies.

bioRxiv · Feb 6, 2021Pharmacology & Toxicology