Author

D. Smiraglia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Assay:proteomics· 1

Frequent Co-Authors

A. M. Rowsam· 1 shared A. Mahpour· 1 shared B. S. Scruggs· 1 shared G. Llimos· 1 shared H. C. Affronti· 1 shared I. Gelman· 1 shared J. J. Jacobi· 1 shared J. Kirk· 1 shared

Activity by Year

2017-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCancer Biology

A. M. Rowsam

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2 papers

Recent·Most cited

Reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer

M. D. Long, P. K. Singh, G. Llimos, J. J. Jacobi, A. M. Rowsam, S. R. Rosario, J. Kirk, H. C. Affronti, M. J. Campbell, D. Smiraglia

This study shows reduced NCOR2 expression accelerates androgen deprivation therapy failure in prostate cancer by promoting DNA hypermethylation and neuroendocrine gene expression.

bioRxiv · Jul 2, 2020Cancer Biology

A novel core promoter element induces bidirectional transcription in CpG island

A. Mahpour, D. Smiraglia, B. S. Scruggs, I. Gelman, T. Ouchi

The paper identifies a conserved core promoter element, CGCG, that drives bidirectional transcription in CpG island promoters and is inhibited by methylation.

bioRxiv · Oct 13, 2017Cell Biology