D. Starenki

powerTCR: a model-based approach to comparative analysis of the clone size distribution of the T cell receptor repertoire

The paper introduces a model-based method to analyze T cell receptor repertoire clone size distributions and applies it to datasets to identify differences across biological conditions.

The expression of class II major histocompatibility molecules on breast tumors delays T cell exhaustion, expands the T cell repertoire and slows tumor growth

This study shows that MHCII expression on breast tumors slows growth, recruits more T cells, expands TCR diversity, and delays exhaustion, but does not prevent exhaustion.