eNOS-induced vascular barrier disruption in retinopathy by c-Src activation and tyrosine phosphorylation of VE-cadherin
T. Ninchoji, D. T. Love, R. Smith, M. Hedlund, D. Vestweber, W. C. Sessa, L. Claesson-Welsh
The paper investigates eNOS's role in retinopathy by showing it disrupts vascular barriers via c-Src and VE-cadherin phosphorylation, and demonstrates that inhibiting NO formation reduces leakage.
bioRxiv · Nov 24, 2020Cell Biology