D. Tranchina

Parallel proteomics and phosphoproteomics defines starvation signal specific processes in cell quiescence

This study uses proteomics and phosphoproteomics to show that carbon and phosphorus starvation trigger distinct but overlapping molecular processes in yeast quiescence.

Spontaneous single-nucleotide substitutions and microsatellite mutations have distinct distributions of fitness effects

This study measures the fitness effects of spontaneous single-nucleotide substitutions and microsatellite mutations in yeast, finding they have distinct distributions of mutational effects on growth rate.

Fluctuating environments maintain genetic diversity through neutral fitness effects and balancing selection

The paper shows fluctuating environments maintain genetic diversity through neutral fitness effects and balancing selection, contrasting with static environments that reduce diversity.