Author

L. Janska

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:cell type annotation· 2 Research Focus:cell-cell communication· 2 Research Focus:development & morphogenesis· 2 Assay:proteomics· 1 Organism:yeast· 1

Frequent Co-Authors

C. Carmona-Fontaine· 2 shared L. Anandi· 2 shared D. Tranchina· 1 shared D. W. Hall· 1 shared G. Guzelsoy· 1 shared J. Garcia· 1 shared J. Liu· 1 shared L. T. Schachtner· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCancer Biology

C. Carmona-Fontaine

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Author profile →

3 papers

Recent·Most cited

Spontaneous single-nucleotide substitutions and microsatellite mutations have distinct distributions of fitness effects

Y. Plavskin, M. S. de Biase, N. Ziv, L. Janska, Y. O. Zhu, D. W. Hall, R. F. Schwarz, D. Tranchina, M. L. Siegal

This study measures the fitness effects of spontaneous single-nucleotide substitutions and microsatellite mutations in yeast, finding they have distinct distributions of mutational effects on growth rate.

bioRxiv · Jul 4, 2023Evolutionary Biology

Direct visualization of emergent metastatic features within an ex vivo model of the tumor microenvironment

L. Anandi, J. Garcia, M. Ros, L. Janska, J. Liu, C. Carmona-Fontaine

The paper introduces an ex vivo model called 3MIC to study metastatic features in tumor cells under various metabolic conditions and stromal interactions, finding that extracellular acidification is more critical than hypoxia in promoting metastasis.

bioRxiv · Jan 9, 2023 · PreprintCancer Biology

The MEMIC: An ex vivo system to model the complexity of the tumor microenvironment

L. Janska, L. Anandi, N. C. Kirchberger, Z. S. Marinkovic, L. T. Schachtner, G. Guzelsoy, C. Carmona-Fontaine

The paper introduces the MEMIC, an ex vivo model of the tumor microenvironment, and demonstrates its ability to study nutrient effects and cell-cell interactions.

bioRxiv · Jan 27, 2021Cancer Biology