D. Tse

Systematic characterization of genome editing in primary T cells reveals proximal genomic insertions and enables machine learning prediction of CRISPR-Cas9 DNA repair outcomes

This study systematically characterizes genome editing in primary T cells, identifies proximal genomic insertions, and develops a machine learning model to predict CRISPR-Cas9 DNA repair outcomes.

Somatic Mutations Render Human Exome and Pathogen DNA more Similar

The paper investigates whether somatic mutations in cancer exomes increase similarity to pathogen peptides and whether specific mutagenic processes enhance immunogenicity.