Author

M. Engler

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:comparative / phylogenetic analysis· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Mirzaiebadizi· 1 shared A. Tchamkerten· 1 shared A. V. Busley· 1 shared B. Wollnik· 1 shared C. Pape· 1 shared D. Tse· 1 shared D. Willbold· 1 shared E. Ebrahimzadeh· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperCell Biology

A. Mirzaiebadizi

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Author profile →

2 papers

Recent·Most cited

LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome

A. V. Busley, O. Gutierrez-Gutierrez, E. Hammer, F. Koitka, A. Mirzaiebadizi, M. Steinegger, C. Pape, L. Boehmer, H. Schroeder, M. Kleinsorge, M. Engler, I. C. Cirstea, L. Gremer, D. Willbold, J. Altmueller, , L. Cyganek

This study identifies a novel LZTR1 variant causing cardiac hypertrophy by altering protein polymerization and ubiquitin ligase function, showing genetic correction can rescue the phenotype.

bioRxiv · Jan 10, 2023Cell Biology

Somatic Mutations Render Human Exome and Pathogen DNA more Similar

A. Tchamkerten, R. Cristescu, E. Ebrahimzadeh, D. Tse, M. Engler

The paper investigates whether somatic mutations in cancer exomes increase similarity to pathogen peptides and whether specific mutagenic processes enhance immunogenicity.

bioRxiv · May 14, 2018Cancer Biology