Vault particles are common contaminants of extracellular vesicle preparations
X. Liu, Z. Nizamudeen, C. J. Hill, C. Parmenter, K. P. Arkill, D. W. Lambert, S. Hunt
The paper shows that vault particles contaminate EV preparations, as vtRNA and MVP are not protected by EV membranes and co-purify with EVs via common isolation methods.
bioRxiv · Nov 9, 2023 · PreprintCell Biology