MYC overrides HIF to regulate proliferating primary cell metabolism in hypoxia
C. A. Copeland, B. A. Olenchock, D. Ziehr, S. McGarrity, K. Leahy, J. D. Young, J. Loscalzo, W. M. Oldham
The paper investigates how MYC overrides HIF to regulate glycolytic flux in hypoxic primary cells, showing MYC's role in modulating HIF-dependent metabolic responses.
bioRxiv · Sep 21, 2020Cell Biology