Radiation-Induced Autophagy Regulates the Fibroblast Mitochondrial Stress Response and Crosstalk with Triple-Negative Breast Cancer Cells
K. C. Corn, S. E. Martello, V. K. Menon, L. S. Britto, K. K. Simmons, Y. K. Mohamed, Y. I. Ivanova, A. A. Ghelmansaraei, S. A. Weidenbach, T. Zhu, E. Krystofiak, J. D. Young, V. Gama, M. Rafat
This study shows that radiation-induced autophagy in fibroblasts alters their mitochondrial stress response, promoting an aggressive phenotype in triple-negative breast cancer cells.
bioRxiv · May 17, 2022Cancer Biology