Author

D.D. Zhang

University of Arizona

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 1

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Approach:experimental assay· 1 Organism:mouse· 1

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Annadurai AnandhaniD· 1 shared Lalitha MadhavaniD· 1 shared Lan Ngoc-NguyeniD· 1 shared Matthew B. DodsoniD· 1 shared W Chen· 1 shared

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2022-2022 · peak 1/yr

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Annadurai AnandhanORCID

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1 paper

Recent·Most cited

α-synuclein over expression, NRF2 suppression, and enhanced ferroptosis creates a vicious cycle of neuronal loss in Parkinson's disease

Annadurai Anandhan, W Chen, Lan Ngoc-Nguyen, Lalitha Madhavan, Matthew B. Dodson, D.D. Zhang

In Parkinson's disease models, alpha-synuclein overexpression sensitizes neurons to ferroptosis, potentially by suppressing NRF2 protein, while Nrf2 loss increases ferroptosis markers, alpha-synuclein pathology, and behavioral deficits.

bioRxiv · Jul 22, 2022 · PreprintNeuroscience