p16High immune cell - controlled disease tolerance as a broad defense and healthspan extending strategy
Francisco Triana-Martínez, Alessandra Pierantoni, Daisy Graça, Veronica Bergo, Alexander Emelyanov, Alexandre Gallerand, Laurent Grosse, Bogdan B. Grigorash, Aikaterini Polyzou, Alexia Castiglione, Shunya Tsuji, Sosuke Nakano, Vesna Brglez, Zakariya Caillot, Pierre Marty, , Dmitry V. Bulavin
This study identifies p16High immune cells as critical for disease tolerance, showing they enhance survival in various conditions and extend healthspan by maintaining low adenosine levels.
Immunity · Mar 26, 2026Peer-reviewedCell Biology