Micro-dissection and integration of long and short reads to create a robust catalog of kidney compartment-specific isoforms
Ridvan Eksi, Daiyao Yi, Hongyang Li, Bradley Godfrey, Lisa R. Mathew, Christopher Lund O'Connor, Markus Bitzer, Matthias Kretzler, Rajasree Menon, Yuanfang Guan
The paper develops a pipeline combining micro-dissection and long/short-read sequencing to identify compartment-specific isoforms in kidney tissue, finding distinct isoform expression in glomerular and tubulo-interstitial compartments.
bioRxiv · Sep 7, 2021 · PreprintBioinformatics