Author

Damien Lajoignie

Lyon 1 Université

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:Drosophila· 3 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Approach:optimal transport· 1 Assay:scRNA-seq· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Hélène Tarayre· 3 shared Séverine Vincent· 3 shared Yad Ghavi-HelmiD· 3 shared Deevitha BalasubramanianiD· 2 shared Juliette Mendes· 2 shared Pedro Borges Pinto· 2 shared Alexia GrassoiD· 1 shared Baptiste AlbertiiD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersGenomics

Hélène Tarayre

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3 papers

Recent·Most cited

Core promoters restrict pleiotropic enhancer inputs to achieve spatiotemporal specificity in gene expression

Margarita Masoura, Deevitha Balasubramanian, C. Moretti, Laëtitia Cadet, Matéo Lison, Hélène Tarayre, Damien Lajoignie, Clara Cretet-Rodeschini, Claudie Carron, Juliette Mendes, Séverine Vincent, Carlos Aguirre Flores, Pedro Borges Pinto, Yad Ghavi-Helm

The paper shows core promoters restrict enhancer inputs to achieve spatiotemporal specificity in gene expression using the Drosophila twist E3 enhancer as a model.

bioRxiv · Sep 23, 2025 · PreprintGenetics

Spatial-scERA: A method for reconstructing spatial single-cell enhancer activity in multicellular organisms

Baptiste Alberti, Séverine Vincent, Isabelle Stévant, Damien Lajoignie, Hélène Tarayre, Juliette Mendes, Sergio Sarnataro, Paul Villoutreix, Yad Ghavi-Helm

Spatial-scERA reconstructs spatial single-cell enhancer activity in multicellular organisms using integrated transcriptomic and spatial data.

Nucleic Acids Research · Jul 19, 2025Peer-reviewedGenomics

Enhancer-promoter interactions form independently of genomic distance and are functional across TAD boundaries

Pedro Borges Pinto, Alexia Grasso, Deevitha Balasubramanian, Séverine Vincent, Hélène Tarayre, Damien Lajoignie, Yad Ghavi-Helm

The paper shows enhancer-promoter interactions can occur across TAD boundaries and large genomic distances, challenging the idea that TADs strictly constrain such interactions.

bioRxiv · Aug 29, 2022 · PreprintGenomics