Author

Dan Liao

National University of Singapore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Genetics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Amanda C. GarfinkeliD· 1 shared Angela C. Tai· 1 shared Barbara A. McDonoughiD· 1 shared Charles S RedwoodiD· 1 shared Christine E. SeidmaniD· 1 shared Christopher N. ToepferiD· 1 shared Hiroko WakimotoiD· 1 shared Hugh C WatkinsiD· 1 shared

Activity by Year

2018-2018 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Amanda C. GarfinkelORCID

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1 paper

Recent·Most cited

MYBPC3 Mutations cause Hypertrophic Cardiomyopathy by Dysregulating Myosin: Implications for Therapy

Christopher N. Toepfer, Hiroko Wakimoto, Amanda C. Garfinkel, Barbara A. McDonough, Dan Liao, Jianming Jiang, Angela C. Tai, Josh M. Gorham, Ida Gjervold Lunde, Mingyue Lun, Thomas L. Lynch, Sakthivel Sadayappan, Charles S Redwood, Hugh C Watkins, Jonathan G. Seidman, Christine E. Seidman

The paper shows that MYBPC3 mutations disrupt myosin relaxation states, leading to hyper-contractility in HCM, and that targeting myosin can alleviate these effects.

bioRxiv · Apr 18, 2018 · PreprintGenetics