Author
Harvard UniversityORCID 0000-0003-0225-6424Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Monika Litviňuková, Carlos N. Talavera-López, Henrike Maatz…·Sarah Amalia Teichmann
The paper characterizes the cellular composition and gene expression of the adult human heart using single-cell transcriptomics, identifying distinct cell types and their functional roles.
Motoshi Hayano, Jae-Hyun Yang, Michael S. Bonkowski…·David A. Sinclair
The paper shows that DNA double-strand breaks induce epigenomic changes that accelerate the aging clock in mammals.
Christopher N. Toepfer, Hiroko Wakimoto, Amanda C. Garfinkel…·Christine E. Seidman
The paper shows that MYBPC3 mutations disrupt myosin relaxation states, leading to hyper-contractility in HCM, and that targeting myosin can alleviate these effects.