Ophthalmate tripeptide is a signaling molecule that regulates striatal neurotransmission
Dana Shevachman, Archana Proddutur, Shweta Sharma, Peter A. LeWitt, György Lür, Amal Alachkar
This study identifies ophthalmate as a striatal neuromodulator that interacts with dopamine and selectively modulates GABA and glutamate release in motor pathways.
bioRxiv · Aug 4, 2026 · PreprintNeuroscience