Author

Peter A. LeWitt

Wayne State UniversityORCID 0000-0002-4976-4445Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Assay:electronic health records· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Bedri RanxhiiD· 2 shared Sokol V. TodiiD· 2 shared Wei‐Ling TsouiD· 2 shared Amal AlachkariD· 1 shared Archana ProdduturiD· 1 shared Dana Shevachman· 1 shared Fatimah H Hussein· 1 shared György LüriD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersNeuroscience

Bedri RanxhiORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Ophthalmate tripeptide is a signaling molecule that regulates striatal neurotransmission

Dana Shevachman, Archana Proddutur, Shweta Sharma, Peter A. LeWitt, György Lür, Amal Alachkar

This study identifies ophthalmate as a striatal neuromodulator that interacts with dopamine and selectively modulates GABA and glutamate release in motor pathways.

bioRxiv · Aug 4, 2026 · PreprintNeuroscience

Chronic alpha-Synuclein Over-Expression and Ceruloplasmin Challenge Promote Distinct Iron and Redox Responses in M17 Cells

Masoumeh Pourhadi, Bedri Ranxhi, Seth P Sukaria, Fatimah H Hussein, Sokol V. Todi, Peter A. LeWitt, Wei‐Ling Tsou

This study investigates how chronic alpha-synuclein over-expression and ceruloplasmin-mediated iron modulation affect iron and redox homeostasis in neuroblastoma cells.

bioRxiv · Jun 16, 2026 · PreprintNeuroscience

Regulation of polyamine interconversion enzymes affects α-Synuclein levels and toxicity in a Drosophila model of Parkinsons disease

Bedri Ranxhi, Zoya R. Bangash, Zachary M. Chbihi, Zaina Qadri, Nazin N. Islam, Sokol V. Todi, Peter A. LeWitt, Wei‐Ling Tsou

This study shows that manipulating polyamine interconversion enzymes in a Drosophila Parkinson's model affects alpha-synuclein levels and toxicity, suggesting a potential therapeutic target.

npj Parkinson s Disease · Aug 6, 2025Peer-reviewedNeuroscience