Identification of subject-specific immunoglobulin alleles from expressed repertoire sequencing data
Daniel Gadala-Maria, Moriah Gidoni, Susanna Marquez, Jason A. Vander Heiden, Justin T. Kos, Corey T. Watson, Kevin C. O’Connor, Gur Yaari, Steven H. Kleinstein
The paper improves the TIgGER algorithm to accurately identify subject-specific immunoglobulin alleles from AIRR-seq data, even when alleles differ by more than 5 SNPs from known database alleles.
Frontiers in Immunology · Feb 13, 2019Peer-reviewedBioinformatics