Evolutionary Origin of the Mammalian Hematopoietic System Found in a Colonial Chordate
Benyamin Rosental, Mark Kowarsky, Jun Seita, Daniel M. Corey, Katherine J. Ishizuka, Karla J. Palmeri, Shih-Yu Chen, Rahul Sinha, Jennifer Okamoto, Gary Mantalas, Lucia Manni, Tal Raveh, D. Nathaniel Clarke, Aaron M. Newman, Norma F. Neff, , Ayelet Voskoboynik
The paper identifies hematopoietic stem cells and related lineages in Botryllus schlosseri, suggesting their evolutionary origin in a common ancestor of tunicates and vertebrates.
bioRxiv · Dec 26, 2017 · PreprintImmunology