Ayelet Voskoboynik

The paper identifies region-specific signaling cues that control stem cell-mediated regeneration in the invertebrate chordate Ciona robusta.

This study maps the anatomical and functional organization of the cholinergic system in Botryllus schlosseri, revealing a dual-effector system coordinating muscular and ciliary networks.

This study identifies a conserved neural stem cell pool driving continuous CNS regeneration in Botryllus schlosseri, showing aging disrupts this process.

The study quantifies survival benefits and germline competition costs of chimerism in Botryllus schlosseri, finding survival advantages outweigh competition costs.

This study investigates age-related changes in germline stem cells (GSCs) in the protochordate Botryllus schlosseri using single-cell RNA sequencing and transplantation assays, revealing that GSCs, not gametes, drive reproductive aging.

The paper shows that pulsatile electrical current improves survival, regeneration, and reproduction in Botryllus schlosseri by altering stem cell and immune activity through transcriptomic changes.

sc-SPLASH enables reference-free discovery in scRNA-seq and spatial transcriptomics, uncovering novel transcriptomic features like V(D)J recombination and secreted repeat proteins.

This study characterizes the transcriptomic and cellular dynamics of whole CNS regeneration in the tunicate Polycarpa mytiligera, identifying key pathways and markers involved in the process.

The paper studies neurodegeneration in the colonial chordate Botryllus schlosseri, finding conserved mechanisms between tunicates and humans.

The paper identifies age-specific circadian gene expression patterns in Botryllus schlosseri and links them to aging phenotypes and pathways.

This study compares molecular and morphological signatures in two developmental pathways of tunicates, finding distinct molecular programs but shared stem cell profiles.

The paper identifies hematopoietic stem cells and related lineages in Botryllus schlosseri, suggesting their evolutionary origin in a common ancestor of tunicates and vertebrates.